Sponsored post from EverydayHealth.com, 11/2025

The older I get, the more pills I have to swallow every morning just to function. The pill case I take on vacation could double as a musical instrument.

So when Dose made supplement drinks to take the place of yet another giant capsule to boost my health, I was eager to give them a try. While I’ve been testing Dose for Your Liver, I also spoke to a board-certified internal medicine doctor and a registered dietitian to get an objective perspective about whether something this tasty can also be as beneficial as the brand claims.

On the surface, Dose shots may seem like a prepackaged version of what you might get at a fancy juice bar, and they do taste pretty similar. The difference is that in Dose, there’s a much higher concentration of the active ingredients and zero sugar, so you don’t have to worry that your sugar intake is canceling out the good stuff.

A balanced diet, plenty of sleep, and regular exercise are ideally all I need to have a healthy liver, experts tell me. But life gets in the way of ideals, doesn’t it? I’m always sabotaging myself with celebratory drinks, missed workouts, family feasts, midnight worry sessions, and more, making me think I could use a nutritional assist to stay on track and feel my best.

Below, I get into the details of how Dose for Your Liver — along with Doses for Cholesterol, Skin, and Immunity — might help you as well as why, after this test, I’ll be renewing my monthly subscription to get these healthy shots delivered right to my door.

Pros

  • Tastes great
  • No sugar
  • Less expensive than fresh juice
  • Science-backed ingredients

Cons

  • Not necessary for everyone
  • Curcumin may stain

Your Dose Order

While Dose provided my bottles for the purpose of this article, it’s pretty easy and relatively inexpensive to get them on your own at DoseDaily.co. A three-pack of 16-ounce (oz) bottles costs $90, which comes to $3.75 per 2-oz shot. If you subscribe to delivery every 24 days, you’ll save 40 percent, paying just $2.25 per shot.

The bottles don’t need to be refrigerated until opened (and last 30 days after that), and your first order comes with a cute metal shot glass for more convenient measuring.

According to the brand, you can take 2 oz once a day for three to four days a week to “combat everyday stressors” from food, medications, alcohol, and unhealthy air. For long-term liver health, Dose recommends one shot daily, and for “liver damage support,” it recommends two shots a day.

Who Needs Dose for Your Liver?

The liver has some very important jobs: It filters harmful substances from your blood, releases bile to aid digestion, stores and releases glucose to regulate blood sugar, and stores and releases other nutrients to regulate your energy levels.

“Your liver is constantly filtering your blood, breaking down medications, hormones, and environmental toxins, and packaging everything so your body can safely get rid of it,” explains Ehsan Ali, MD, a board-certified physician in internal medicine in the Los Angeles area who is also known as the Beverly Hills Concierge Doctor. (Everyday Health consulted Dr. Ali for information about the liver and various supplements, but he has no association with Dose, and his participation in this article is not meant to be an endorsement.)

Most of the time, your liver works just fine on its own, and there’s no need to detoxify it — that’s the liver’s actual job. But there are a number of factors that can harm it, including viruses (such as hepatitis A, B, and C), heavy alcohol consumption, obesity, diabetes, certain medications, autoimmune diseases, and some hereditary diseases.

Twenty-five percent of adults have metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease. MASLD can eventually lead to liver failure if untreated. Plus, like so much of the rest of your body, the liver starts to decline as you age.

If you suspect that you’re experiencing an acute or chronic liver disease, seek medical care and advice immediately. But if you’re just looking for ways to help your body along, taking supplements like Dose can give you a boost. The drink contains concentrated ingredients that have clinically proven benefits to the liver, and it’s so much easier to swallow on a regular basis than most pills.

“There isn’t a magic reset button or some deep-clean cycle [for the liver],” Ali says. “It’s more about giving the liver what it needs to keep doing the work it already does exceptionally well.”

Dose for Your Liver Ingredients

While Windsor, Colorado–based nutritionist Brittany Scanniello, RD, reiterates that “the best way to support liver function is through good habits: a balanced diet, regular exercise, maintaining a healthy weight, limiting alcohol, and staying hydrated,” she does see the value in the ingredients of Dose for Your Liver. (Scanniello is also not associated with Dose, and her participation here does not indicate an endorsement.) She and Ali helped me review each of them.

  • Milk Thistle “Milk thistle, commonly known as silymarin in the supplement space, is one of the better-studied herbal agents for supporting liver health, specifically in the presence of liver injury such as fatty liver, hepatitis, or cirrhosis,” Scanniello says, cautioning that most evidence is for people with compromised livers. Ali agrees, adding, “It has antioxidant properties and may help protect liver cells from damage.” Milk thistle also has anti-inflammatory properties. Studies show it can help regulate glucose levels in people with type 2 diabetes.
  • Curcumin While traditional medicine has long used turmeric for its healthful properties, Dose has extracted curcumin molecules from it in such a way that the brand claims 2 oz of the drink has the equivalent of 17 cold-pressed turmeric shots. “Curcumin is another strong contender; it’s a powerful anti-inflammatory, and chronic inflammation plays a big role in many liver issues,” Ali says.
  • Dandelion Root We may call it a weed, but compounds in its roots have been shown to have anti-diabetes properties. “Dandelion has been used traditionally for liver and gallbladder health, but the modern science is less clear,” Ali adds.

Ginger Ali says ginger is primarily beneficial as an aid to digestion, and we know it’s great for nausea. There’s also some evidence that ginger can help with diabetes, cardiovascular health, the immune system, weight loss, and more.

My Dose Experience

A shot of Dose for Your Liver really does taste like something I’d get at a juice bar. The juice contains orange juice extract and monk fruit extract for sweetness, while the turmeric and ginger add just a little bit of zing without being at all spicy.

I’m grateful it doesn’t have any artificial sweeteners, which I really have no tolerance for. Though I liked the taste when I tried it unrefrigerated right after it arrived, it’s even better after being refrigerated. I’ve found myself looking forward to drinking this once a day.

How does it make me feel? I do have healthy liver function, according to my most recent physical, and it’s only been a week since I started drinking Dose, so I don’t know what the long-term effects of it will be yet.

What I can say is that the first time I tried Dose was after indulging in some beer with friends. That night, instead of the insomnia that alcohol normally gives me, I slept straight through the night. And I’ve been sleeping well every night since, despite work and holiday stress. For someone like me who’s in the first stages of perimenopause, this is huge.

Is Dose Worth It?

Going back to my previous calculations, if you get a subscription to Dose, you’ll be paying just $2.20 per shot. I haven’t seen prices like that at a juice bar since the ’90s. Add the fact that each shot contains a far more concentrated amount of beneficial ingredients than a regular juice, and this is a fantastic deal.

While I haven’t tested my liver enzymes since trying Dose, the brand’s clinical studies show some impressive results.

After eight weeks, participants who took Dose for Your Liver in a double-blind study saw an average of 50 percent reduction in their AST levels and 52 percent reduction in their ALT levels (enzymes measured to show liver health). In a second study, after three months of taking Dose, 88 percent saw a positive impact in AST and ALT levels, and 94 percent saw a positive impact in ALP levels (another measure of liver health).

If you have reason to worry about your liver health, you should absolutely seek the advice of a healthcare provider before doing anything else. Dose is not meant to treat, cure, or prevent disease. But this is one way you can take a positive step toward boosting your liver health without medication, so I think it’s worth a try.

Other Dose Products

dose for cholestrol
Dose

The other Dose supplement drinks are Dose for Cholesterol, Dose for Immunity, and Dose for Your Skin. I haven’t tried them, but their ingredients have real scientific evidence behind them. Here’s a brief summary of each:

Dose for Cholesterol is formulated with amla, an Indian fruit that “may help lower LDL cholesterol and support overall heart health due to its antioxidant properties,” Ali says. Other antioxidants in the drink include CoQ10, lycopene, and black pepper. Folic acid, curcumin, pomegranate, and niacinamide round out this ingredients list.

Dose for Immunity contains vitamin C from elderberry, acerola, amla, and lemon. Ginger is an anti-inflammatory, and zinc and licorice have been shown to stimulate the immune system.
Dose for Your Skin blends aloe vera, amla, Centella asiatica, licorice, orange, and sea buckthorn. “Sea buckthorn is another ingredient with strong clinical evidence for skin hydration and barrier support when taken orally,” Scanniello says.
“It has a unique blend of omega-7 fatty acids, carotenoids, and vitamin E, which work to not only help strengthen the skin’s barrier but also reduce dryness and improve elasticity.”

FAQ

Is a liquid supplement better than one in pill form?

According to both Ali and Scanniello, there’s no medical reason to prefer a supplement drink over a tablet or capsule, since the body absorbs nutrients at about the same rate either way.

There is one big benefit to Dose shots, however: “The real advantage of a drink is simply that it’s easy to take, and people tend to be more consistent with things that feel enjoyable,” Ali says. “If someone genuinely likes the experience of a drink over a pill, that alone can make it more effective for them.”

When is the best time to take Dose?

You can drink Dose shots at any time of day, and they’re pretty gentle on the stomach. But if you’re the type of person who does get sensitive to certain ingredients, it’s easy enough to drink with or after a meal.

What else should I do to improve my liver health?

“Reducing alcohol is huge,” Ali says. “Eating a diet rich in vegetables, fiber, and healthy fats helps your liver metabolize everything more efficiently. Staying hydrated, exercising regularly, and keeping your cholesterol and blood sugar in healthy ranges all lighten the workload on the liver.”